T-705 (favipiravir) activity against lethal H5N1 influenza A viruses

The neuraminidase inhibitors oseltamivir and zanamivi are used to treat H5N1 influenza. However, oseltamivir-resistant H5N1 viruses have been isolated from oseltamivir-treated patients. Moreover, reassortment between H5N1 viruses and oseltamvir-resistant human H1N1 viruses currently circulating coul...

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Detalhes bibliográficos
Main Authors: Kiso, Maki, Takahashi, Kazumi, Sakai-Tagawa, Yuko, Shinya, Kyoko, Sakabe, Saori, Le, Quynh Mai, Ozawa, Makoto, Furuta, Yousuke, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818889/
https://ncbi.nlm.nih.gov/pubmed/20080770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909603107
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