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Gab2 Promotes Hematopoietic Stem Cell Maintenance and Self-Renewal Synergistically with STAT5

BACKGROUND: Grb2-associated binding (Gab) adapter proteins play major roles in coordinating signaling downstream of hematopoietic cytokine receptors. In hematopoietic cells, Gab2 can modulate phosphatidylinositol–3 kinase and mitogen associated protein kinase activities and regulate the long-term mu...

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Bibliografiske detaljer
Main Authors: Li, Geqiang, Wang, Zhengqi, Miskimen, Kristy L., Zhang, Yi, Tse, William, Bunting, Kevin D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818849/
https://ncbi.nlm.nih.gov/pubmed/20161778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009152
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