Repeatability and Reproducibility in Proteomic Identifications by Liquid Chromatography—Tandem Mass Spectrometry

The complexity of proteomic instrumentation for LC-MS/MS introduces many possible sources of variability. Data-dependent sampling of peptides constitutes a stochastic element at the heart of discovery proteomics. Although this variation impacts the identification of peptides, proteomic identificatio...

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Main Authors: Tabb, David L., Vega-Montoto, Lorenzo, Rudnick, Paul A., Variyath, Asokan Mulayath, Ham, Amy-Joan L., Bunk, David M., Kilpatrick, Lisa E., Billheimer, Dean D., Blackman, Ronald K., Cardasis, Helene L., Carr, Steven A., Clauser, Karl R., Jaffe, Jacob D., Kowalski, Kevin A., Neubert, Thomas A., Regnier, Fred E., Schilling, Birgit, Tegeler, Tony J., Wang, Mu, Wang, Pei, Whiteaker, Jeffrey R., Zimmerman, Lisa J., Fisher, Susan J., Gibson, Bradford W., Kinsinger, Christopher R., Mesri, Mehdi, Rodriguez, Henry, Stein, Steven E., Tempst, Paul, Paulovich, Amanda G., Liebler, Daniel C., Spiegelman, Cliff
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818771/
https://ncbi.nlm.nih.gov/pubmed/19921851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr9006365
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