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A milk protein gene promoter directs the expression of human tissue plasminogen activator cDNA to the mammary gland in transgenic mice.

Whey acidic protein (WAP) is a major whey protein in mouse milk. Its gene is expressed in the lactating mammary gland and is inducible by steroid and peptide hormones. A series of transgenic mice containing a hybrid gene in which human tissue plasminogen activator (tPA) cDNA is under the control of...

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Bibliographic Details
Main Authors: Pittius, C W, Hennighausen, L, Lee, E, Westphal, H, Nicols, E, Vitale, J, Gordon, K
Format: Artigo
Language:Inglês
Published: 1988
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC281867/
https://ncbi.nlm.nih.gov/pubmed/2842753
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