Enhanced Antitumor Efficacy of Vasculostatin (Vstat120) Expressing Oncolytic HSV-1

Oncolytic viral (OV) therapy is a promising therapeutic modality for brain tumors. Vasculostatin (Vstat120) is the cleaved and secreted extracellular fragment of brain-specific angiogenesis inhibitor 1 (BAI1), a brain-specific receptor. To date, the therapeutic efficacy of Vstat120 delivery into est...

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Main Authors: Hardcastle, Jayson, Kurozumi, Kazuhiko, Dmitrieva, Nina, Sayers, Martin P, Ahmad, Sarwat, Waterman, Peter, Weissleder, Ralph, Chiocca, E Antonio, Kaur, Balveen
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2009
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818668/
https://ncbi.nlm.nih.gov/pubmed/19844198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.232
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