A repressor heterodimer binds to a chimeric operator.

Replacement of the solvent-exposed residues of the DNA recognition helix of the 434 repressor with the corresponding residues of the P22 repressor generates a hybrid protein, 434R[alpha 3(P22R)], which binds specifically to P22 operators. We show here that a new DNA-binding specificity is generated...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Hollis, M, Valenzuela, D, Pioli, D, Wharton, R, Ptashne, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281859/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3413061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.5834
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