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A repressor heterodimer binds to a chimeric operator.

Replacement of the solvent-exposed residues of the DNA recognition helix of the 434 repressor with the corresponding residues of the P22 repressor generates a hybrid protein, 434R[alpha 3(P22R)], which binds specifically to P22 operators. We show here that a new DNA-binding specificity is generated...

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Bibliografiske detaljer
Main Authors: Hollis, M, Valenzuela, D, Pioli, D, Wharton, R, Ptashne, M
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC281859/
https://ncbi.nlm.nih.gov/pubmed/3413061
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