A repressor heterodimer binds to a chimeric operator.
Replacement of the solvent-exposed residues of the DNA recognition helix of the 434 repressor with the corresponding residues of the P22 repressor generates a hybrid protein, 434R[alpha 3(P22R)], which binds specifically to P22 operators. We show here that a new DNA-binding specificity is generated...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1988
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281859/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3413061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.5834 |
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