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The Synthesis and Evaluation of Flavone and Isoflavone Chimeras of Novobiocin and Derrubone
[Image: see text] The natural products novobiocin and derrubone have both demonstrated Hsp90 inhibition and structure–activity relationships have been established for each scaffold. Given these compounds share several key structural features, we hypothesized that incorporation of elements from each...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818389/ https://ncbi.nlm.nih.gov/pubmed/19932969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.10.061 |
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