IL-1RA blocks E. coli-induced suppression of Arc and long-term memory in aged F344 × BN F1 rats

In normal aging, a peripheral immune challenge induces a sensitized and protracted neuroinflammatory response in parallel with long-term memory (LTM) impairments. Proinflammatory mediators of neuroinflammation impair LTM, synaptic plasticity and LTP. The immediate early gene Arc is considered a crit...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Frank, Matthew G., Barrientos, Ruth M., Hein, Amy M., Biedenkapp, Joseph C., Watkins, Linda R., Maier, Steven F.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818379/
https://ncbi.nlm.nih.gov/pubmed/19822205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2009.10.005
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares