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IL-1RA injected intra-cisterna magna confers extended prophylaxis against lipopolysaccharide-induced neuroinflammatory and sickness responses
IL-1RA has been used intra-cerebrally to ameliorate neuroinflammatory responses. The present study explored the possibility that the bioactivity of IL-1RA administered intra-cerebrally may be prolonged in the CNS. hIL-1RA was detected in hippocampus from 2 h to 14 d post-ICM treatment. hIL-1RA ameli...
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| 出版年: | J Neuroimmunol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5652306/ https://ncbi.nlm.nih.gov/pubmed/22871632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2012.07.010 |
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