A carregar...

Vacuolization and alterations of lysosomal membrane proteins in cochlear marginal cells contribute to hearing loss in neuraminidase 1 – deficient mice

The neuraminidase-1 (Neu1) knockout mouse model is a phenocopy of the lysosomal storage disease (LSD) sialidosis, characterized by multisystemic and neuropathic symptoms, including hearing loss. We have characterized the auditory defects in Neu1(−/−) mice and found that hearing loss involves both co...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wu, Xudong, Steigelman, Katherine A, Bonten, Erik, Hu, Huimin, He, Wenxuan, Ren, Tianying, Zuo, Jian, d’Azzo, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818351/
https://ncbi.nlm.nih.gov/pubmed/19857571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2009.10.008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!