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Partial rescue of postnatal growth plate abnormalities in Ihh mutants by expression of a constitutively active PTH/PTHrP receptor

Indian hedgehog (Ihh) is essential for chondrocyte proliferation/differentiation and osteoblast differentiation during prenatal endochondral bone formation. Ihh expression in postnatal chondrocytes has a non-redundant role in maintaining a growth plate and sustaining trabecular bone after birth. Los...

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Detalhes bibliográficos
Main Authors: Maeda, Yukiko, Schipani, Ernestina, Densmore, Michael J., Lanske, Beate
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818229/
https://ncbi.nlm.nih.gov/pubmed/19761883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2009.09.009
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