Alpha-1-Antitrypsin Deficiency and Smoking as Risk Factors for Mismatch Repair Deficient Colorectal Cancer: a Study from the Colon Cancer Family Registry

In a previous study, alpha-1-antitrypsin (A1AT) deficiency alleles were found to be over represented among individuals with microsatellite unstable (MSI-high) colorectal cancers, and this was most significant in former or current smokers. We evaluated this association in a larger case-control study,...

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Hlavní autoři: Lindor, Noralane M., Yang, Ping, Evans, Ilonka, Schowalter, Karen, De Andrade, Mariza, Li, Jia, Jeavons, Elysia, Peterson, Gloria, Gallinger, Steve, Bapat, Bharati, Hopper, John, Jass, Jeremy, Jenkins, Mark, Templeton, Allyson, Potter, John, Newcomb, Polly A., LeMarchand, Loic, Grove, John, Haile, Robert, Baron, John, Seminara, Daniela, Limburg, Paul, Thibodeau, Stephen N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818220/
https://ncbi.nlm.nih.gov/pubmed/19853488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2009.09.010
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