Lower Cancer Incidence in Amsterdam-I Criteria Families Without Mismatch Repair Deficiency: Familial Colorectal Cancer Type X

CONTEXT: Approximately 60% of families that meet the Amsterdam-I criteria (AC-I) for hereditary nonpolyposis colorectal cancer (HNPCC) have a hereditary abnormality in a DNA mismatch repair (MMR) gene. Cancer incidence in AC-I families with MMR gene mutations is reported to be very high, but cancer...

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Detalhes bibliográficos
Principais autores: Lindor, Noralane M., Rabe, Kari, Petersen, Gloria M., Haile, Robert, Casey, Graham, Baron, John, Gallinger, Steve, Bapat, Bharati, Aronson, Melyssa, Hopper, John, Jass, Jeremy, LeMarchand, Loic, Grove, John, Potter, John, Newcomb, Polly, Terdiman, Jonathan P., Conrad, Peggy, Moslein, Gabriella, Goldberg, Richard, Ziogas, Argyrios, Anton-Culver, Hoda, de Andrade, Mariza, Siegmund, Kim, Thibodeau, Stephen N., Boardman, Lisa A., Seminara, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933042/
https://ncbi.nlm.nih.gov/pubmed/15855431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.293.16.1979
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