MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8

Senescence is a cellular program that irreversibly arrests the proliferation of damaged cells and induces the secretion of the inflammatory mediators IL- 6 and IL-8 which are part of a larger senescence associated secretory phenotype (SASP). We screened quiescent and senescent human fibroblasts for...

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Main Authors: Bhaumik, Dipa, Scott, Gary K., Schokrpur, Shiruyeh, Patil, Christopher K., Orjalo, Arturo V., Rodier, Francis, Lithgow, Gordon J., Campisi, Judith
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818025/
https://ncbi.nlm.nih.gov/pubmed/20148189
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