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The conserved active site tryptophan of thioredoxin has no effect on its redox properties
In Staphylococcus aureus thioredoxin (Trx) it has been shown that mutation of the conserved active site tryptophan residue (Trp28) has a large effect on the protein stability, on the pKa of the nucleophilic cysteine and on the redox potential. Since these effects can either be due to the partially u...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2817855/ https://ncbi.nlm.nih.gov/pubmed/19902501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.269 |
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