Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production

BACKGROUND: Nikkomycins are a group of peptidyl nucleoside antibiotics produced by Streptomyces ansochromogenes. They are competitive inhibitors of chitin synthase and show potent fungicidal, insecticidal, and acaricidal activities. Nikkomycin X and Z are the main components produced by S. ansochrom...

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Bibliografski detalji
Glavni autori: Liao, Guojian, Li, Jine, Li, Lei, Yang, Haihua, Tian, Yuqing, Tan, Huarong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817672/
https://ncbi.nlm.nih.gov/pubmed/20096125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-9-6
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