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Identification of novel tylosin analogues generated by a wblA disruption mutant of Streptomyces ansochromogenes

BACKGROUND: Streptomyces, as the main source of antibiotics, has been intensively exploited for discovering new drug candidates to combat the evolving pathogens. Disruption of wblA, an actinobacteria-specific gene controlling major developmental transition, can cause the alteration of phenotype and...

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Bibliografiske detaljer
Udgivet i:Microb Cell Fact
Main Authors: Lu, Cheng, Liao, Guojian, Zhang, Jihui, Tan, Huarong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630966/
https://ncbi.nlm.nih.gov/pubmed/26525981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0359-5
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