The small 11kDa nonstructural protein of human parvovirus B19 plays a key role in inducing apoptosis during B19 virus infection of primary erythroid progenitor cells

Human parvovirus B19 (B19V) infection shows a strong erythroid tropism and drastically destroys erythroid progenitor cells, thus leading to most of the disease outcomes associated with B19V infection. In this study, we systematically examined the 3 B19V nonstructural proteins, 7.5kDa, 11kDa, and NS1...

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Detalhes bibliográficos
Main Authors: Chen, Aaron Yun, Zhang, Elizabeth Yan, Guan, Wuxiang, Cheng, Fang, Kleiboeker, Steve, Yankee, Thomas M., Qiu, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817633/
https://ncbi.nlm.nih.gov/pubmed/19861680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-04-215756
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