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Human Parvovirus B19 Infection Causes Cell Cycle Arrest of Human Erythroid Progenitors at Late S Phase That Favors Viral DNA Replication

Human parvovirus B19 (B19V) infection has a unique tropism to human erythroid progenitor cells (EPCs) in human bone marrow and the fetal liver. It has been reported that both B19V infection and expression of the large nonstructural protein NS1 arrested EPCs at a cell cycle status with a 4 N DNA cont...

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Detalhes bibliográficos
Main Authors: Luo, Yong, Kleiboeker, Steve, Deng, Xuefeng, Qiu, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838147/
https://ncbi.nlm.nih.gov/pubmed/24049177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02333-13
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