Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex

Productive infection of human parvovirus B19 (B19V) exhibits high tropism for burst forming unit erythroid (BFU-E) and colony forming unit erythroid (CFU-E) progenitor cells in human bone marrow and fetal liver. This exclusive restriction of the virus replication to human erythroid progenitor cells...

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Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Ganaie, Safder S., Zou, Wei, Xu, Peng, Deng, Xuefeng, Kleiboeker, Steve, Qiu, Jianming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426800/
https://ncbi.nlm.nih.gov/pubmed/28459842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006370
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