Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex

Productive infection of human parvovirus B19 (B19V) exhibits high tropism for burst forming unit erythroid (BFU-E) and colony forming unit erythroid (CFU-E) progenitor cells in human bone marrow and fetal liver. This exclusive restriction of the virus replication to human erythroid progenitor cells...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Ganaie, Safder S., Zou, Wei, Xu, Peng, Deng, Xuefeng, Kleiboeker, Steve, Qiu, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426800/
https://ncbi.nlm.nih.gov/pubmed/28459842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006370
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