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Down-regulation of beta-adrenergic receptors: agonist-induced reduction in receptor mRNA levels.
Incubation of DDT1 MF-2 hamster vas deferens cells with beta-adrenergic agonists results in a time- and concentration-dependent decreases in both beta-adrenergic receptor (beta AR) responsiveness and receptor number. Receptor mRNA levels were quantified by DNA-excess solution hybridization by using...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1988
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281679/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2899321/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.14.5021 |
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