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Down-regulation of beta-adrenergic receptors: agonist-induced reduction in receptor mRNA levels.

Incubation of DDT1 MF-2 hamster vas deferens cells with beta-adrenergic agonists results in a time- and concentration-dependent decreases in both beta-adrenergic receptor (beta AR) responsiveness and receptor number. Receptor mRNA levels were quantified by DNA-excess solution hybridization by using...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Hadcock, J R, Malbon, C C
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1988
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281679/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2899321/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.14.5021
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