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Down-regulation of beta-adrenergic receptors: agonist-induced reduction in receptor mRNA levels.

Incubation of DDT1 MF-2 hamster vas deferens cells with beta-adrenergic agonists results in a time- and concentration-dependent decreases in both beta-adrenergic receptor (beta AR) responsiveness and receptor number. Receptor mRNA levels were quantified by DNA-excess solution hybridization by using...

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Bibliografiske detaljer
Main Authors: Hadcock, J R, Malbon, C C
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC281679/
https://ncbi.nlm.nih.gov/pubmed/2899321
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