Hormone-receptor interactions are noncooperative: application to the beta-adrenergic receptor.
We have developed kinetic methods with which we have demonstrated that the negatively cooperative hormone-binding model is untenable for the insulin receptor system. These methods have led others to the same conclusion for the thyrotropin and nerve growth factor receptors. We report here the applica...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1980
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349830/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6254021/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.7.4340 |
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