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Regulation of Gene Expression in Hepatic Cells by the Mammalian Target of Rapamycin (mTOR)
BACKGROUND: We investigated mTOR regulation of gene expression by studying rapamycin effect in two hepatic cell lines, the non-tumorigenic WB-F344 cells and the tumorigenic WB311 cells. The latter are resistant to the growth inhibitory effects of rapamycin, thus providing us with an opportunity to s...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2816708/ https://ncbi.nlm.nih.gov/pubmed/20140209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009084 |
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