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Fas/CD95 Deficiency in Apc(Min/+) Mice Increases Intestinal Tumor Burden
BACKGROUND: Fas, a member of the tumor necrosis family, is responsible for initiating the apoptotic pathway when bound to its ligand, Fas-L. Defects in the Fas-mediated apoptotic pathway have been reported in colorectal cancer. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, a variant of the A...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2816700/ https://ncbi.nlm.nih.gov/pubmed/20140201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009070 |
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