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The Overlap of Small Molecule and Protein Binding Sites within Families of Protein Structures

Protein–protein interactions are challenging targets for modulation by small molecules. Here, we propose an approach that harnesses the increasing structural coverage of protein complexes to identify small molecules that may target protein interactions. Specifically, we identify ligand and protein b...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Davis, Fred P., Sali, Andrej
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816688/
https://ncbi.nlm.nih.gov/pubmed/20140189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000668
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