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The Overlap of Small Molecule and Protein Binding Sites within Families of Protein Structures
Protein–protein interactions are challenging targets for modulation by small molecules. Here, we propose an approach that harnesses the increasing structural coverage of protein complexes to identify small molecules that may target protein interactions. Specifically, we identify ligand and protein b...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2816688/ https://ncbi.nlm.nih.gov/pubmed/20140189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000668 |
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