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Mapping the 3D structures of small molecule binding sites

BACKGROUND: Analysis of the 3D structures of protein–ligand binding sites can provide valuable insights for drug discovery. Binding site comparison (BSC) studies can be employed to elucidate the function of orphan proteins or to predict the potential for polypharmacology. Many previous binding site...

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Publicat a:J Cheminform
Autors principals: Meyers, Joshua, Brown, Nathan, Blagg, Julian
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395517/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-016-0180-0
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