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Influence of omega-6 PUFA arachidonic acid and bone marrow adipocytes on metastatic spread from prostate cancer

BACKGROUND: Prostate cancer (CaP) preferentially metastasises to the bone, and we have previously shown that the poly-unsaturated fatty acid (PUFA) arachidonic acid (AA) is a potent stimulator of CaP invasion. Here we present that AA promotes CaP invasion by inducing bone marrow adipocyte formation....

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Autors principals: Brown, M D, Hart, C, Gazi, E, Gardner, P, Lockyer, N, Clarke, N
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816655/
https://ncbi.nlm.nih.gov/pubmed/19997104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605481
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