Lack of association between oestrogen receptor polymorphisms and change in bone mineral density with tamoxifen therapy

BACKGROUND: Tamoxifen, a selective oestrogen receptor (ER) modulator, increases bone mineral density (BMD) in postmenopausal women and decreases BMD in premenopausal women. We hypothesised that inherited variants in candidate genes involved in oestrogen signalling and tamoxifen metabolism might be a...

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Bibliografiske detaljer
Main Authors: Henry, N L, Nguyen, A, Azzouz, F, Li, L, Robarge, J, Philips, S, Cao, D, Skaar, T C, Rae, J M, Storniolo, A M, Flockhart, D A, Hayes, D F, Stearns, V
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Clinical Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816645/
https://ncbi.nlm.nih.gov/pubmed/19953095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605460
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