Aldosterone Upregulates Connective Tissue Growth Factor Gene Expression via p38 MAPK Pathway and Mineralocorticoid Receptor in Ventricular Myocytes

The effect of aldosterone on connective tissue growth factor (CTGF) was examined in rat embryonic ventricular myocytes. Upon aldosterone treatment, CTGF expression was significantly increased in a dose and time-dependent manner. To explore the molecular mechanism for this upregulation, we examined t...

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Detalhes bibliográficos
Main Authors: Lee, Young-Sam, Kim, Jeong-A, Kim, Koung Li, Jang, Hyung-Suk, Kim, Jeong-Min, Lee, Jae-Young, Shin, In-Soon, Lee, Jung-Sun, Suh, Wonhee, Choi, Jin-Ho, Jeon, Eun-Seok, Byun, Jonghoe, Kim, Duk-Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Medical Sciences 2004
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816296/
https://ncbi.nlm.nih.gov/pubmed/15608389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2004.19.6.805
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