Aldosterone Upregulates Connective Tissue Growth Factor Gene Expression via p38 MAPK Pathway and Mineralocorticoid Receptor in Ventricular Myocytes

The effect of aldosterone on connective tissue growth factor (CTGF) was examined in rat embryonic ventricular myocytes. Upon aldosterone treatment, CTGF expression was significantly increased in a dose and time-dependent manner. To explore the molecular mechanism for this upregulation, we examined t...

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Bibliographic Details
Main Authors: Lee, Young-Sam, Kim, Jeong-A, Kim, Koung Li, Jang, Hyung-Suk, Kim, Jeong-Min, Lee, Jae-Young, Shin, In-Soon, Lee, Jung-Sun, Suh, Wonhee, Choi, Jin-Ho, Jeon, Eun-Seok, Byun, Jonghoe, Kim, Duk-Kyung
Format: Artigo
Language:Inglês
Published: The Korean Academy of Medical Sciences 2004
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816296/
https://ncbi.nlm.nih.gov/pubmed/15608389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2004.19.6.805
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