Aldosterone Upregulates Connective Tissue Growth Factor Gene Expression via p38 MAPK Pathway and Mineralocorticoid Receptor in Ventricular Myocytes

The effect of aldosterone on connective tissue growth factor (CTGF) was examined in rat embryonic ventricular myocytes. Upon aldosterone treatment, CTGF expression was significantly increased in a dose and time-dependent manner. To explore the molecular mechanism for this upregulation, we examined t...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Young-Sam, Kim, Jeong-A, Kim, Koung Li, Jang, Hyung-Suk, Kim, Jeong-Min, Lee, Jae-Young, Shin, In-Soon, Lee, Jung-Sun, Suh, Wonhee, Choi, Jin-Ho, Jeon, Eun-Seok, Byun, Jonghoe, Kim, Duk-Kyung
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Korean Academy of Medical Sciences 2004
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816296/
https://ncbi.nlm.nih.gov/pubmed/15608389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2004.19.6.805
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