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Clinical significance of EGFR amplification and the aberrant EGFRvIII transcript in conventionally treated astrocytic gliomas

The aim of this study was to evaluate the clinical value of assessing EGFR amplification, and the common 5′ rearrangement of EGFR resulting in the EGFRvIII transcript in astrocytic gliomas. The data from 221 tumours was correlated with patient survival. The majority of previous studies evaluated amp...

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Hlavní autoři: Liu, Lu, Bäcklund, L. Magnus L., Nilsson, Bo R., Grandér, D., Ichimura, Koichi, Goike, Helena M., Collins, V. Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815848/
https://ncbi.nlm.nih.gov/pubmed/16133418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-005-0700-2
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