Flavopiridol, Fludarabine, and Rituximab in Mantle Cell Lymphoma and Indolent B-Cell Lymphoproliferative Disorders

PURPOSE: Flavopiridol downmodulates antiapoptotic proteins associated with resistance to fludarabine and rituximab and is effective against p53-mutated chronic lymphocytic leukemia (CLL). We conducted a phase I study of flavopiridol, fludarabine, and rituximab (FFR) in patients with mantle-cell lymp...

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Autors principals: Lin, Thomas S., Blum, Kristie A., Fischer, Diane Beth, Mitchell, Sarah M., Ruppert, Amy S., Porcu, Pierluigi, Kraut, Eric H., Baiocchi, Robert A., Moran, Mollie E., Johnson, Amy J., Schaaf, Larry J., Grever, Michael R., Byrd, John C.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2010
Matèries:
Original Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815704/
https://ncbi.nlm.nih.gov/pubmed/20008633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.24.1570
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