Flavopiridol, Fludarabine, and Rituximab in Mantle Cell Lymphoma and Indolent B-Cell Lymphoproliferative Disorders

PURPOSE: Flavopiridol downmodulates antiapoptotic proteins associated with resistance to fludarabine and rituximab and is effective against p53-mutated chronic lymphocytic leukemia (CLL). We conducted a phase I study of flavopiridol, fludarabine, and rituximab (FFR) in patients with mantle-cell lymp...

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Bibliografiset tiedot
Päätekijät: Lin, Thomas S., Blum, Kristie A., Fischer, Diane Beth, Mitchell, Sarah M., Ruppert, Amy S., Porcu, Pierluigi, Kraut, Eric H., Baiocchi, Robert A., Moran, Mollie E., Johnson, Amy J., Schaaf, Larry J., Grever, Michael R., Byrd, John C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Clinical Oncology 2010
Aiheet:
Original Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815704/
https://ncbi.nlm.nih.gov/pubmed/20008633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.24.1570
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