Combination bortezomib and rituximab treatment affects multiple survival and death pathways to promote apoptosis in mantle cell lymphoma

Mantle cell lymphoma (MCL) is a distinct histologic subtype of B cell non-Hodgkins lymphoma (NHL) associated with an aggressive clinical course. Inhibition of the ubiquitin-proteasome pathway modulates survival and proliferation signals in MCL and has shown clinical benefit in this disease. This has...

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Autores principales: Alinari, Lapo, White, Valerie L, Earl, Christian T, Ryan, Timothy P, Johnston, Jeffrey S, Dalton, James T, Ferketich, Amy K, Lai, Raymond, Lucas, David M, Porcu, Pierluigi, Blum, Kristie A, Byrd, John C, Baiocchi, Robert A
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715189/
https://ncbi.nlm.nih.gov/pubmed/20046572
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