A selective eradication of human nonhereditary breast cancer cells by phenanthridine-derived polyADP-ribose polymerase inhibitors

INTRODUCTION: PARP-1 (polyADP-ribose polymerase-1) is known to be activated in response to DNA damage, and activated PARP-1 promotes DNA repair. However, a recently disclosed alternative mechanism of PARP-1 activation by phosphorylated externally regulated kinase (ERK) implicates PARP-1 in a vast nu...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Inbar-Rozensal, Dana, Castiel, Asher, Visochek, Leonid, Castel, David, Dantzer, Françoise, Izraeli, Shai, Cohen-Armon, Malka
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2009
Предметы:
Research article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815540/
https://ncbi.nlm.nih.gov/pubmed/19891779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2445
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы