The Unique Kinetics of Iron Release from Transferrin: The Role of Receptor, Lobe-Lobe Interactions and Salt at Endosomal pH

The transferrins are a family of bilobal iron-binding proteins that play the crucial role of binding ferric iron and keeping it in solution, thereby controlling the levels of this important metal. Human serum transferrin (hTF) carries one iron in each of two similar lobes. Understanding the detailed...

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Bibliographic Details
Main Authors: Byrne, Shaina L., Chasteen, N. Dennis, Steere, Ashley N., Mason, Anne B.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815179/
https://ncbi.nlm.nih.gov/pubmed/19917294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.11.023
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