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REPLACEMENT WITH GABAERGIC STEROID PRECURSORS RESTORES THE ACUTE ETHANOL WITHDRAWAL PROFILE IN ADX/GDX MICE

The neurosteroid allopregnanolone (ALLO) is a progesterone metabolite that is one of a family of neuroactive steroids (NAS) that are potent positive allosteric modulators of γ-aminobutyric acid(A) (GABA(A)) receptors. These GABAergic NAS are produced peripherally (in the adrenals and gonads) and cen...

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Autors principals: Kaufman, KR, Tanchuck, MA, Strong, MN, Finn, DA
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815158/
https://ncbi.nlm.nih.gov/pubmed/20004707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.11.075
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