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Inhibition of 5α-Reduced Steroid Biosynthesis Impedes Acquisition of Ethanol Drinking in Male C57BL/6J Mice

BACKGROUND: Allopregnanolone (ALLO) is a physiologically-relevant neurosteroid modulator of GABA(A) receptors, and it exhibits a psychopharmacological profile that closely resembles the post-ingestive effects of ethanol. The 5α-reductase inhibitor finasteride (FIN), which inhibits biosynthesis of AL...

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Hlavní autoři: Ford, Matthew M., Yoneyama, Naomi, Strong, Moriah N., Fretwell, Andrea, Tanchuck, Michelle, Finn, Deborah A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847609/
https://ncbi.nlm.nih.gov/pubmed/18565155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2008.00718.x
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