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Inhibition of 5α-Reduced Steroid Biosynthesis Impedes Acquisition of Ethanol Drinking in Male C57BL/6J Mice
BACKGROUND: Allopregnanolone (ALLO) is a physiologically-relevant neurosteroid modulator of GABA(A) receptors, and it exhibits a psychopharmacological profile that closely resembles the post-ingestive effects of ethanol. The 5α-reductase inhibitor finasteride (FIN), which inhibits biosynthesis of AL...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847609/ https://ncbi.nlm.nih.gov/pubmed/18565155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2008.00718.x |
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