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Functional characterization of LIT1, the Leishmania amazonensis ferrous iron transporter
Leishmania amazonensis LIT1 was identified based on homology with IRT1, a ferrous iron transporter from Arabidopsis thaliana. Δlit1 Leishmania amazonensis are defective in intracellular replication and lesion formation in vivo, a virulence phenotype attributed to defective intracellular iron acquisi...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2009
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2815141/ https://ncbi.nlm.nih.gov/pubmed/20025906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2009.12.003 |
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