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PARTICIPATION OF SIGNALING PATHWAYS IN THE DEREPRESSION OF LUTEINIZING HORMONE RECEPTOR TRANSCRIPTION

The luteinizing hormone receptor (LHR) transcription is subject to an epigenetic regulatory mode whereby the proximal Sp1 site acts as an anchor to recruit histone deacetylases (HDAC)1/2 and the Sin3A co-repressor complex. This results in promoter-localized histone hypoacetylation that contributes t...

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Bibliografske podrobnosti
Main Authors: Dufau, Maria L., Liao, Mingjuan, Zhang, Ying
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815110/
https://ncbi.nlm.nih.gov/pubmed/19464346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2009.05.005
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