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Unlocking Repression of the Human Luteinizing Hormone Receptor Gene by Trichostatin A-induced Cell-specific Phosphatase Release

Our previous studies demonstrated that the histone deacetylase inhibitor, trichostatin A (TSA), induces derepression of the human luteinizing hormone receptor (LHR) gene by de-recruitment of the pRB homologue p107 repressor from the promoter in JAR and MCF-7 cancer cells. TSA initiates a mechanism w...

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Autori principali: Zhang, Ying, Liao, Mingjuan, Dufau, Maria L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527114/
https://ncbi.nlm.nih.gov/pubmed/18596044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801878200
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