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Repression of the Luteinizing Hormone Receptor Gene Promoter by Cross Talk among EAR3/COUP-TFI, Sp1/Sp3, and TFIIB
Transcription of luteinizing hormone receptor (LHR) gene is activated by Sp1/Sp3 at two Sp1 sites and is repressed by nuclear orphan receptors EAR2 and EAR3 through a direct-repeat (DR) motif. To elucidate the mechanism of the orphan receptor-mediated gene repression, we explored the functional conn...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC193922/ https://ncbi.nlm.nih.gov/pubmed/12972613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.19.6958-6972.2003 |
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