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Coordinated Changes in DNA Methylation and Histone Modifications Regulate Silencing/Derepression of Luteinizing Hormone Receptor Gene Transcription

We have previously demonstrated that transcription of the luteinizing hormone receptor (LHR) gene is subject to repression by histone deacetylation at its promoter region, where a histone deacetylase (HDAC)/mSin3A complex is anchored at a proximal Sp1 site. The present studies have shown that epigen...

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Détails bibliographiques
Auteurs principaux: Zhang, Ying, Fatima, Naheed, Dufau, Maria L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234307/
https://ncbi.nlm.nih.gov/pubmed/16135786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.18.7929-7939.2005
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