Coordinated Changes in DNA Methylation and Histone Modifications Regulate Silencing/Derepression of Luteinizing Hormone Receptor Gene Transcription

We have previously demonstrated that transcription of the luteinizing hormone receptor (LHR) gene is subject to repression by histone deacetylation at its promoter region, where a histone deacetylase (HDAC)/mSin3A complex is anchored at a proximal Sp1 site. The present studies have shown that epigen...

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Detalles Bibliográficos
Main Authors: Zhang, Ying, Fatima, Naheed, Dufau, Maria L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234307/
https://ncbi.nlm.nih.gov/pubmed/16135786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.18.7929-7939.2005
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