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Calpain inhibition impairs TNF-α-mediated neutrophil adhesion, arrest and oxidative burst

Proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-α), are increased in many chronic inflammatory disorders, including rheumatoid arthritis, and contribute to recruitment of neutrophils into areas of inflammation. TNF-α induces a stop signal that promotes neutrophil firm adhesion an...

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Библиографические подробности
Главные авторы: Wiemer, Andrew J., Lokuta, Mary A., Surfus, Jill C., Wernimont, Sarah A., Huttenlocher, Anna
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814964/
https://ncbi.nlm.nih.gov/pubmed/19889458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.10.002
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