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Calpain regulates neutrophil chemotaxis

Cell polarization is required for directed cell migration. We investigated the role of the calcium-dependent protease calpain during neutrophil chemotaxis and found that calpain inhibition induced neutrophil adhesion, polarization, and rapid chemokinesis in the absence of exogenous activators. Resti...

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Bibliografiske detaljer
Main Authors: Lokuta, M. A., Nuzzi, P. A., Huttenlocher, A.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC153038/
https://ncbi.nlm.nih.gov/pubmed/12649322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0636533100
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