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Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
Using a model of lethal oral infection with Toxoplasma gondii, we examined the fate of both induced and natural regulatory T (Treg) cells in the face of strong inflammatory responses occurring in a tolerogenic-prone environment. We found that during highly T helper 1 (Th1) cell-polarized mucosal imm...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814877/ https://ncbi.nlm.nih.gov/pubmed/19896394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.10.001 |
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